CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.410 | Cholesterol Oxidase; domain 2 |
|
3.30.410.40 |
Domain Context
CATH Clusters
| Superfamily | 3.30.410.40 |
| Functional Family |
Enzyme Information
| 1.1.3.17 |
Choline oxidase.
based on mapping to UniProt Q7X2H8
Choline + 2 O(2) + H(2)O = betaine + 2 H(2)O(2).
-!- In many bacteria, plants and animals, the osmoprotectant betaine is synthesized using different enzymes to catalyze the conversion of (1) choline into betaine aldehyde and (2) betaine aldehyde into betaine. -!- In plants, the first reaction is catalyzed by EC 1.14.15.7, whereas in animals and many bacteria, it is catalyzed by either EC 1.1.99.1 or EC 1.1.3.17. -!- The enzyme involved in the second step, EC 1.2.1.8, appears to be the same in those plants, animals and bacteria that use two separate enzymes.
|
UniProtKB Entries (1)
| Q7X2H8 |
CHOX_ARTGO
Arthrobacter globiformis
Choline oxidase
|
PDB Structure
| PDB | 3LJP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase.
Biochemistry
|
