CATH Domain 3l95X01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.300	GMP Synthetase; Chain A, domain 3
	3.30.300.320

Domain Context

CATH Clusters

Superfamily	3.30.300.320
Functional Family	Neurogenic locus notch 1

Enzyme Information

UniProtKB Entries (1)

NOTC1_HUMAN

Homo sapiens

Neurogenic locus notch homolog protein 1

PDB Structure

PDB	3L95
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Therapeutic antibody targeting of individual Notch receptors. Wu, Y., Cain-Hom, C., Choy, L., Hagenbeek, T.J., de Leon, G.P., Chen, Y., Finkle, D., Venook, R., Wu, X., Ridgway, J., Schahin-Reed, D., Dow, G.J., Shelton, A., Stawicki, S., Watts, R.J., Zhang, J., Choy, R., Howard, P., Kadyk, L., Yan, M., Zha, J., Callahan, C.A., Hymowitz, S.G., Siebel, C.W. Nature