1 keywords

CATH Domain 3l1bA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Bile acid receptor isoform 4

Enzyme Information

UniProtKB Entries (1)

Q96RI1
NR1H4_HUMAN
Homo sapiens
Bile acid receptor

PDB Structure

PDB 3L1B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates.
Lundquist, J.T., Harnish, D.C., Kim, C.Y., Mehlmann, J.F., Unwalla, R.J., Phipps, K.M., Crawley, M.L., Commons, T., Green, D.M., Xu, W., Hum, W.T., Eta, J.E., Feingold, I., Patel, V., Evans, M.J., Lai, K., Borges-Marcucci, L., Mahaney, P.E., Wrobel, J.E.
J.Med.Chem.