CATH Domain 3kpeA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.300

Domain Context

CATH Clusters

Superfamily	1.20.5.300
Functional Family

Enzyme Information

UniProtKB Entries (1)

FUS_HRSVA

Human respiratory syncytial virus A2

Fusion glycoprotein F0

PDB Structure

PDB	3KPE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. Roymans, D., De Bondt, H.L., Arnoult, E., Geluykens, P., Gevers, T., Van Ginderen, M., Verheyen, N., Kim, H., Willebrords, R., Bonfanti, J.F., Bruinzeel, W., Cummings, M.D., van Vlijmen, H., Andries, K. Proc.Natl.Acad.Sci.USA