CATH Domain 3klsA12

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.690	Alpha-macroglobulin, receptor-binding domain

Domain Context

CATH Clusters

Superfamily	Alpha-macroglobulin, receptor-binding domain
Functional Family	Complement C5

Enzyme Information

UniProtKB Entries (1)

CO5_HUMAN

Homo sapiens

Complement C5

PDB Structure

PDB	3KLS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Laursen, N.S., Gordon, N., Hermans, S., Lorenz, N., Jackson, N., Wines, B., Spillner, E., Christensen, J.B., Jensen, M., Fredslund, F., Bjerre, M., Sottrup-Jensen, L., Fraser, J.D., Andersen, G.R. Proc.Natl.Acad.Sci.USA