CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.572 | Thymidylate Synthase; Chain A |
|
3.30.572.10 | Thymidylate synthase/dCMP hydroxymethylase domain |
Domain Context
CATH Clusters
| Superfamily | Thymidylate synthase/dCMP hydroxymethylase domain |
| Functional Family |
Enzyme Information
| 2.1.1.45 |
Thymidylate synthase.
based on mapping to UniProt O62584
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
|
UniProtKB Entries (1)
| O62584 |
TYS1_ENCCU
Encephalitozoon cuniculi GB-M1
Thymidylate synthase 1/2
|
PDB Structure
| PDB | 3KGB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of thymidylate synthase 1/2 from Encephalitozoon cuniculi at 2.2 A resolution
TO BE PUBLISHED
|