CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family Fructose-1,6-bisphosphatase class 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt P09467
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

P09467
F16P1_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase 1

PDB Structure

PDB 3KBZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors.
Tsukada, T., Takahashi, M., Takemoto, T., Kanno, O., Yamane, T., Kawamura, S., Nishi, T.
Bioorg.Med.Chem.Lett.
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