CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.2250 | B family DNA polymerase, N domain, alpha/beta motif |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.2250 |
| Functional Family | DNA polymerase |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P21189
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
| P21189 |
DPO2_ECOLI
Escherichia coli K-12
DNA polymerase II
|
PDB Structure
| PDB | 3K5M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.)
|
