CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1340 | dopa decarboxylase, N-terminal domain |
|
1.20.1340.10 | dopa decarboxylase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | dopa decarboxylase, N-terminal domain |
| Functional Family | Histidine decarboxylase |
Enzyme Information
| 4.1.1.28 |
Aromatic-L-amino-acid decarboxylase.
based on mapping to UniProt P05031
(1) L-dopa = dopamine + CO(2). (2) 5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO(2).
-!- Also acts on other aromatic L-amino acids, including L-tryptophan. -!- Formerly EC 4.1.1.26 and EC 4.1.1.27.
|
UniProtKB Entries (1)
| P05031 |
DDC_DROME
Drosophila melanogaster
Aromatic-L-amino-acid decarboxylase
|
PDB Structure
| PDB | 3K40 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase
Plos One
|