CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1260 | Ferritin |
|
1.20.1260.70 |
Domain Context
CATH Clusters
| Superfamily | 1.20.1260.70 |
| Functional Family |
Enzyme Information
| 2.7.7.n6 |
Guanine phosphate-protein transferase.
based on mapping to UniProt Q5ZSQ3
GTP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)-(5'-guanylyl)- L-tyrosine.
-!- The enzyme from Legionella also functions as EC 2.7.7.n1.
|
| 2.7.7.n1 |
Protein adenylyltransferase.
based on mapping to UniProt Q5ZSQ3
(1) ATP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-tyrosine. (2) ATP + [protein]-L-threonine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-threonine.
|
UniProtKB Entries (2)
| Q5ZSQ3 |
DRRA_LEGPH
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Multifunctional virulence effector protein DrrA
|
| Q9H0U4 |
RAB1B_HUMAN
Homo sapiens
Ras-related protein Rab-1B
|
PDB Structure
| PDB | 3JZA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.
Mol.Cell
|
