CATH Classification
Domain Context
CATH Clusters
Superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
Functional Family | Phosphodiesterase |
Enzyme Information
3.1.4.35 |
3',5'-cyclic-GMP phosphodiesterase.
based on mapping to UniProt O76074
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.
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3.1.4.35 |
3',5'-cyclic-GMP phosphodiesterase.
based on mapping to UniProt P51160
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.
|
UniProtKB Entries (1)
P51160 |
PDE6C_HUMAN
Homo sapiens
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
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PDB Structure
PDB | 3JWQ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J.
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