CATH Classification
Level | CATH Code | Description |
---|---|---|
6 | Special | |
6.10 | Helix non-globular | |
6.10.250 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | |
6.10.250.2210 |
Domain Context
CATH Clusters
Superfamily | 6.10.250.2210 |
Functional Family |
Enzyme Information
UniProtKB Entries (1)
D9N170 |
D9N170_PLAFA
Plasmodium falciparum
Bifunctional dihydrofolate reductase-thymidylate synthase
|
PDB Structure
PDB | 3JSU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate
Antimicrob.Agents Chemother.
|