CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Functional Family Ferredoxin--NADP reductase, apicoplast

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt C6KT68
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.

UniProtKB Entries (1)

C6KT68
FENR_PLAF7
Plasmodium falciparum 3D7
Ferredoxin--NADP reductase, apicoplast

PDB Structure

PDB 3JQR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis
Crobu, D., Canevari, G., Milani, M., Pandini, V., Vanoni, M.A., Bolognesi, M., Zanetti, G., Aliverti, A.
Biochemistry
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