CATH Domain 3jqcC00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

Q581W1_TRYB2

Trypanosoma brucei brucei TREU927

Pteridine reductase, putative

PDB Structure

PDB	3JQC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. Tulloch, L.B., Martini, V.P., Iulek, J., Huggan, J.K., Lee, J.H., Gibson, C.L., Smith, T.K., Suckling, C.J., Hunter, W.N. J.Med.Chem.