CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.25 | Alpha Horseshoe |
|
1.25.40 | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
|
1.25.40.20 | Ankyrin repeat-containing domain |
Domain Context
CATH Clusters
| Superfamily | Ankyrin repeat-containing domain |
| Functional Family | integrin-linked protein kinase |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13418
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| Q13418 |
ILK_HUMAN
Homo sapiens
Integrin-linked protein kinase
|
PDB Structure
| PDB | 3IXE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase.
J.Struct.Biol.
|
