CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family Pyruvate kinase

Enzyme Information

2.7.1.40
Pyruvate kinase.
based on mapping to UniProt Q27686
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).

UniProtKB Entries (1)

Q27686
KPYK_LEIME
Leishmania mexicana
Pyruvate kinase

PDB Structure

PDB 3IS4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase
Morgan, H.P., McNae, I.W., Hsin, K.Y., Michels, P.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.
Acta Crystallogr.,Sect.F
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