CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.3380 | Sec63 N-terminal domain-like fold |
|
1.10.3380.10 | Sec63 N-terminal domain-like domain |
Domain Context
CATH Clusters
| Superfamily | Sec63 N-terminal domain-like domain |
| Functional Family | Pre-mRNA-splicing helicase BRR2 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt P32639
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
| P32639 |
BRR2_YEAST
Saccharomyces cerevisiae S288C
Pre-mRNA-splicing helicase BRR2
|
PDB Structure
| PDB | 3IM1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
To be Published
|