CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.418 | Actin-binding Protein, T-fimbrin; domain 1 |
|
1.10.418.10 | Calponin-like domain |
Domain Context
CATH Clusters
| Superfamily | Calponin-like domain |
| Functional Family | IQ motif containing GTPase activating protein 1 |
Enzyme Information
UniProtKB Entries (1)
| P46940 |
IQGA1_HUMAN
Homo sapiens
Ras GTPase-activating-like protein IQGAP1
|
PDB Structure
| PDB | 3I6X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The IQGAP1 N-terminus Forms Dimers and the Dimer Interface is Required for Binding F-actin and Ca2+/calmodulin.
Biochemistry
|
