CATH Classification

Domain Context

CATH Clusters

Superfamily TolB, C-terminal domain
Functional Family

Enzyme Information

3.1.8.2
Diisopropyl-fluorophosphatase.
based on mapping to UniProt Q7SIG4
Diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + fluoride.
-!- Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases). -!- Inhibited by chelating agents. -!- Related to EC 3.1.8.1. -!- Formerly EC 3.8.2.1.

UniProtKB Entries (1)

Q7SIG4
DFPA_LOLVU
Loligo vulgaris
Diisopropyl-fluorophosphatase

PDB Structure

PDB 3I1C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.
Siegel, J.B., Zanghellini, A., Lovick, H.M., Kiss, G., Lambert, A.R., St Clair, J.L., Gallaher, J.L., Hilvert, D., Gelb, M.H., Stoddard, B.L., Houk, K.N., Michael, F.E., Baker, D.
Science