CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.110 | Pnp Oxidase; Chain A | |
2.30.110.10 | Electron Transport, Fmn-binding Protein; Chain A |
Domain Context
CATH Clusters
Superfamily | Electron Transport, Fmn-binding Protein; Chain A |
Functional Family | PNPO isoform 11 |
Enzyme Information
1.4.3.5 |
Pyridoxal 5'-phosphate synthase.
based on mapping to UniProt Q9NVS9
(1) Pyridoxamine 5'-phosphate + H(2)O + O(2) = pyridoxal 5'-phosphate + NH(3) + H(2)O(2). (2) Pyridoxine 5'-phosphate + O(2) = pyridoxal 5'-phosphate + H(2)O(2).
-!- In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
|
UniProtKB Entries (1)
Q9NVS9 |
PNPO_HUMAN
Homo sapiens
Pyridoxine-5'-phosphate oxidase
|
PDB Structure
PDB | 3HY8 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder
J.Biol.Chem.
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