CATH Classification

Domain Context

CATH Clusters

Superfamily Calponin-like domain
Functional Family Filamin-B isoform C

Enzyme Information

UniProtKB Entries (1)

P21333
FLNA_HUMAN
Homo sapiens
Filamin-A

PDB Structure

PDB 3HOR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Clark, A.R., Sawyer, G.M., Robertson, S.P., Sutherland-Smith, A.J.
Hum.Mol.Genet.