CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.130 | Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 |
|
2.30.130.10 | PUA domain |
Domain Context
CATH Clusters
| Superfamily | PUA domain |
| Functional Family | Probable tRNA pseudouridine synthase B |
Enzyme Information
| 5.4.99.25 |
tRNA pseudouridine(55) synthase.
based on mapping to UniProt Q7LWY0
tRNA uridine(55) = tRNA pseudouridine(55).
-!- Pseudourine synthase TruB from Escherichia coli specifically modifies uridine(55) in tRNA molecules. -!- The bifunctional archaeal enzyme also catalyzes the pseudouridylation of uridine(54). -!- It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in E.coli tRNAs by thymine.
|
UniProtKB Entries (1)
| Q8U160 |
RL7A_PYRFU
Pyrococcus furiosus DSM 3638
50S ribosomal protein L7Ae
|
PDB Structure
| PDB | 3HJW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
Nat.Struct.Mol.Biol.
|