CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.20 | Single Sheet | |
2.20.28 | Rubrerythrin, domain 2 | |
2.20.28.20 | Methionyl-tRNA synthetase, Zn-domain |
Domain Context
CATH Clusters
Superfamily | Methionyl-tRNA synthetase, Zn-domain |
Functional Family | Methionine--tRNA ligase |
Enzyme Information
6.1.1.10 |
Methionine--tRNA ligase.
based on mapping to UniProt P00959
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
|
UniProtKB Entries (1)
P00959 |
SYM_ECOLI
Escherichia coli K-12
Methionine--tRNA ligase
|
PDB Structure
PDB | 3H9C |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol.
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