CATH Classification

Domain Context

CATH Clusters

Superfamily Aconitase, domain 4
Functional Family 3-isopropylmalate dehydratase small subunit

Enzyme Information

4.2.1.33
3-isopropylmalate dehydratase.
based on mapping to UniProt P9WK95
(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
-!- Forms part of the leucine-biosynthesis pathway. -!- Brings about the interconversion of the two isomers of isopropylmalate.

UniProtKB Entries (1)

P9WK95
LEUD_MYCTU
Mycobacterium tuberculosis H37Rv
3-isopropylmalate dehydratase small subunit

PDB Structure

PDB 3H5J
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis
Manikandan, K., Geerlof, A., Zozulya, A.V., Svergun, D.I., Weiss, M.S.
Proteins