CATH Classification
Domain Context
CATH Clusters
| Superfamily | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| Functional Family |
Enzyme Information
| 1.1.1.27 |
L-lactate dehydrogenase.
based on mapping to UniProt Q5HJD7
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
|
UniProtKB Entries (1)
| Q5HJD7 |
LDH1_STAAC
Staphylococcus aureus subsp. aureus COL
L-lactate dehydrogenase 1
|
PDB Structure
| PDB | 3H3J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate
To be Published
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