1 keywords

CATH Domain 3gluA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1600 SIR2/SIRT2 'Small Domain'
Homologous Superfamily 3.30.1600.10 SIR2/SIRT2 'Small Domain'

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family NAD-dependent deacetylase sirtuin-3, mitochondrial

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q9NTG7

UniProtKB Entries (1)

Q9NTG7
SIR3_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

PDB Structure

PDB 3GLU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Choy, W., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B.
J.Biol.Chem.