CATH Domain 3gliI02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.60

Domain Context

CATH Clusters

Superfamily	1.10.8.60
Functional Family	DNA polymerase III subunit gamma/tau

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt P06710

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P06710

DPO3X_ECOLI

Escherichia coli K-12

DNA polymerase III subunit tau

PDB Structure

PDB	3GLI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Simonetta, K.R., Kazmirski, S.L., Goedken, E.R., Cantor, A.J., Kelch, B.A., McNally, R., Seyedin, S.N., Makino, D.L., O'Donnell, M., Kuriyan, J. Cell(Cambridge,Mass.)