CATH Classification
Domain Context
CATH Clusters
| Superfamily | RIG-I-like receptor, C-terminal regulatory domain |
| Functional Family | Interferon-induced with helicase C domain 1 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt Q9BYX4
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
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UniProtKB Entries (1)
| Q9BYX4 |
IFIH1_HUMAN
Homo sapiens
Interferon-induced helicase C domain-containing protein 1
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PDB Structure
| PDB | 3GA3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the C-terminal domain of human MDA5
To be Published
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