CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1150 | Aspartate Aminotransferase, domain 1 |
|
3.90.1150.10 | Aspartate Aminotransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aspartate Aminotransferase, domain 1 |
| Functional Family | Serine hydroxymethyltransferase |
Enzyme Information
| 2.1.2.1 |
Glycine hydroxymethyltransferase.
based on mapping to UniProt P0A825
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.
-!- Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine.
|
UniProtKB Entries (1)
| P0A825 |
GLYA_ECOLI
Escherichia coli K-12
Serine hydroxymethyltransferase
|
PDB Structure
| PDB | 3G8M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase.
Biochemistry
|
