CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.70 | Box |
|
3.70.10 | Proliferating Cell Nuclear Antigen |
|
3.70.10.10 |
Domain Context
CATH Clusters
| Superfamily | 3.70.10.10 |
| Functional Family | Cell cycle checkpoint protein RAD1 |
Enzyme Information
| 3.1.11.2 |
Exodeoxyribonuclease III.
based on mapping to UniProt O60671
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Has endonucleolytic activity near apurinic sites on DNA. -!- Similar enzyme: Haemophilus influenzae exonuclease. -!- Formerly EC 3.1.4.27.
|
UniProtKB Entries (1)
| O60671 |
RAD1_HUMAN
Homo sapiens
Cell cycle checkpoint protein RAD1
|
PDB Structure
| PDB | 3G65 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
Mol.Cell
|
