CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt A7GBG3
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

A7GBG3
BXF_CLOBL
Clostridium botulinum F str. Langeland
Botulinum neurotoxin type F

PDB Structure

PDB 3FUQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Fu, Z., Chen, C., Barbieri, J.T., Kim, J.J., Baldwin, M.R.
Biochemistry
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