CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.1.1.80 |
Isopropanol dehydrogenase (NADP(+)).
based on mapping to UniProt P14941
Propan-2-ol + NADP(+) = acetone + NADPH.
-!- Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
|
| 1.1.1.80 |
Isopropanol dehydrogenase (NADP(+)).
based on mapping to UniProt P25984
Propan-2-ol + NADP(+) = acetone + NADPH.
-!- Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
|
UniProtKB Entries (2)
| P25984 |
ADH_CLOBE
Clostridium beijerinckii
NADP-dependent isopropanol dehydrogenase
|
| P14941 |
ADH_THEBR
Thermoanaerobacter brockii
NADP-dependent isopropanol dehydrogenase
|
PDB Structure
| PDB | 3FPL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms
Biochemistry
|
