CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.20 | Severin |
|
3.40.20.10 | Severin |
Domain Context
CATH Clusters
| Superfamily | Severin |
| Functional Family | gelsolin isoform X2 |
Enzyme Information
UniProtKB Entries (2)
| P68135 |
ACTS_RABIT
Oryctolagus cuniculus
Actin, alpha skeletal muscle
|
| P06396 |
GELS_HUMAN
Homo sapiens
Gelsolin
|
PDB Structure
| PDB | 3FFK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
Proc.Natl.Acad.Sci.USA
|
