CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.1060 | Taq DNA Polymerase; Chain T, domain 4 | |
1.20.1060.10 | Taq DNA Polymerase; Chain T, domain 4 |
Domain Context
CATH Clusters
Superfamily | Taq DNA Polymerase; Chain T, domain 4 |
Functional Family | DNA polymerase I |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P52026
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
P52026 |
DPO1_GEOSE
Geobacillus stearothermophilus
DNA polymerase I
|
PDB Structure
PDB | 3EYZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis.
Structure
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