CATH Domain 3et2A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Peroxisome proliferator-activated receptor delta

Enzyme Information

UniProtKB Entries (1)

PPARD_HUMAN

Homo sapiens

Peroxisome proliferator-activated receptor delta

PDB Structure

PDB	3ET2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Artis, D.R., Lin, J.J., Zhang, C., Wang, W., Mehra, U., Perreault, M., Erbe, D., Krupka, H.I., England, B.P., Arnold, J., Plotnikov, A.N., Marimuthu, A., Nguyen, H., Will, S., Signaevsky, M., Kral, J., Cantwell, J., Settachatgull, C., Yan, D.S., Fong, D., Oh, A., Shi, S., Womack, P., Powell, B., Habets, G., West, B.L., Zhang, K.Y., Milburn, M.V., Vlasuk, G.P., Hirth, K.P., Nolop, K., Bollag, G., Ibrahim, P.N., Tobin, J.F. Proc.Natl.Acad.Sci.USA