CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.200 | Peptidase S8/S53 domain |
Domain Context
CATH Clusters
| Superfamily | Peptidase S8/S53 domain |
| Functional Family | Tripeptidyl-peptidase 1 preproprotein |
Enzyme Information
| 3.4.14.9 |
Tripeptidyl-peptidase I.
based on mapping to UniProt O14773
Release of an N-terminal tripeptide from a polypeptide, but also has endopeptidase activity.
-!- A lysosomal enzyme that is active at acidic pH. -!- Belongs to peptidase family S53. -!- Formerly EC 3.4.14.8.
|
UniProtKB Entries (1)
| O14773 |
TPP1_HUMAN
Homo sapiens
Tripeptidyl-peptidase 1
|
PDB Structure
| PDB | 3EE6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis
J.Biol.Chem.
|