CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
1.20.5.1010 | TRPM, tetramerisation domain |
Domain Context
CATH Clusters
| Superfamily | TRPM, tetramerisation domain |
| Functional Family | Transient receptor potential cation channel subfamily M member 7 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q925B3
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| Q925B3 |
TRPM7_RAT
Rattus norvegicus
Transient receptor potential cation channel subfamily M member 7
|
PDB Structure
| PDB | 3E7K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray crystal structure of a TRPM assembly domain reveals an antiparallel four-stranded coiled-coil.
J.Mol.Biol.
|
