CATH Domain 3e3yA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.600	ECO RV Endonuclease; Chain A
	3.40.600.10	DNA mismatch repair MutH/Restriction endonuclease, type II

Domain Context

CATH Clusters

Superfamily	DNA mismatch repair MutH/Restriction endonuclease, type II
Functional Family

Enzyme Information

3.1.21.4

Type II site-specific deoxyribonuclease.

based on mapping to UniProt P17743

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P17743

T2C2_HAEIF

Haemophilus influenzae

Type-2 restriction enzyme HincII

PDB Structure

PDB	3E3Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	DNA distortion and specificity in a sequence-specific endonuclease. Babic, A.C., Little, E.J., Manohar, V.M., Bitinaite, J., Horton, N.C. J.Mol.Biol.