CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Tryptase beta-2

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q16651

UniProtKB Entries (1)

Q16651
PRSS8_HUMAN
Homo sapiens
Prostasin

PDB Structure

PDB 3E16
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.
Tully, D.C., Vidal, A., Chatterjee, A.K., Williams, J.A., Roberts, M.J., Petrassi, H.M., Spraggon, G., Bursulaya, B., Pacoma, R., Shipway, A., Schumacher, A.M., Danahay, H., Harris, J.L.
Bioorg.Med.Chem.Lett.
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