CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.10 | Thrombin, subunit H | |
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
Superfamily | Trypsin-like serine proteases |
Functional Family | Tryptase beta-2 |
Enzyme Information
3.4.21.- |
Serine endopeptidases.
based on mapping to UniProt Q16651
|
UniProtKB Entries (1)
Q16651 |
PRSS8_HUMAN
Homo sapiens
Prostasin
|
PDB Structure
PDB | 3E16 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.
Bioorg.Med.Chem.Lett.
|