CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.166
23S rRNA (uridine(2552)-2'-O)-methyltransferase.
based on mapping to UniProt Q97C13
S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = S-adenosyl-L- homocysteine + 2'-O-methyluridine(2552) in 23S rRNA.
-!- The enzyme catalyzes the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA.

UniProtKB Entries (1)

Q97C13
RLME_THEVO
Thermoplasma volcanium GSS1
Ribosomal RNA large subunit methyltransferase E

PDB Structure

PDB 3DOU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Methyltransferase Involved in Cell Division from Thermoplasma Volcanicum
Patskovsky, Y., Ozyurt, S., Dickey, M., Hu, S., Bain, K., Wasserman, S., Sauder, J.M., Burley, S.K., Almo, S.C.
To be Published