CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q15047
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q15047
SETB1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETDB1

PDB Structure

PDB 3DLM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1.
Dombrovski, L., Amaya, M.F., Loppnau, P., Bochkarev, A., Min, J., Wu, H.
To be Published