CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2440 | Secreted effector protein SifA fold |
|
3.30.2440.10 | Secreted effector protein SifA |
Domain Context
CATH Clusters
| Superfamily | Secreted effector protein SifA |
| Functional Family | SPI-2 type III secretion system effector SifA |
Enzyme Information
UniProtKB Entries (2)
| Q8IWE5 |
PKHM2_HUMAN
Homo sapiens
Pleckstrin homology domain-containing family M member 2
|
| Q56061 |
SIFA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Secreted effector protein SifA
|
PDB Structure
| PDB | 3CXB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation
Cell Host Microbe
|
