CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Ribosomal RNA large subunit methyltransferase I |
Enzyme Information
| 2.1.1.191 |
23S rRNA (cytosine(1962)-C(5))-methyltransferase.
based on mapping to UniProt P75876
S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methylcytosine(1962) in 23S rRNA.
-!- The enzyme specifically methylates cytosine(1962) at C(5) in 23S rRNA.
|
UniProtKB Entries (1)
| P75876 |
RLMI_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase I
|
PDB Structure
| PDB | 3C0K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes
J.Mol.Biol.
|