CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.970 | Ribonuclease HI; Chain A |
|
3.40.970.10 | Ribonuclease H1, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H1, N-terminal domain |
| Functional Family | Ribonuclease H1 |
Enzyme Information
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt O60930
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
| O60930 |
RNH1_HUMAN
Homo sapiens
Ribonuclease H1
|
PDB Structure
| PDB | 3BSU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
Embo J.
|