CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.30 | Gcn5-related N-acetyltransferase (GNAT) |
Domain Context
CATH Clusters
| Superfamily | 3.40.630.30 |
| Functional Family | Diamine acetyltransferase 1 |
Enzyme Information
| 2.3.1.57 |
Diamine N-acetyltransferase.
based on mapping to UniProt P48026
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.
|
UniProtKB Entries (1)
| P48026 |
SAT1_MOUSE
Mus musculus
Diamine acetyltransferase 1
|
PDB Structure
| PDB | 3BJ7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
Biochemistry
|
