CATH Domain 3bftA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.10	Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily	Periplasmic binding protein-like II
Functional Family	Glutamate receptor ionotropic, kainate 2

Enzyme Information

UniProtKB Entries (1)

GRIA2_RAT

Rattus norvegicus

Glutamate receptor 2

PDB Structure

PDB	3BFT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. Beich-Frandsen, M., Pickering, D.S., Mirza, O., Johansen, T.N., Greenwood, J., Vestergaard, B., Schousboe, A., Gajhede, M., Liljefors, T., Kastrup, J.S. J.Med.Chem.