CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1500 | oxygen-dependent coproporphyrinogen oxidase |
|
3.40.1500.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.1500.20 |
| Functional Family | Red chlorophyll catabolite reductase, chloroplastic |
Enzyme Information
| 1.3.7.12 |
Red chlorophyll catabolite reductase.
based on mapping to UniProt Q8LDU4
Primary fluorescent chlorophyll catabolite + 2 oxidized ferredoxin [iron- sulfur] cluster = red chlorophyll catabolite + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+).
-!- The enzyme participates in chlorophyll degradation, which occurs during leaf senescence and fruit ripening in higher plants. -!- The reaction requires reduced ferredoxin, which is generated from NADPH produced either through the pentose-phosphate pathway or by the action of photosystem I. -!- This reaction takes place while red chlorophyll catabolite is still bound to EC 1.14.15.17. -!- Depending on the plant species used as the source of enzyme, one of two possible C-1 epimers of primary fluorescent chlorophyll catabolite (pFCC), pFCC-1 or pFCC-2, is normally formed, with all genera or species within a family producing the same isomer. -!- After modification and export, pFCCs are eventually imported into the vacuole, where the acidic environment causes their non-enzymic conversion into colorless breakdown products called non-fluorescent chlorophyll catabolites (NCCs). -!- Formerly EC 1.3.1.80.
|
UniProtKB Entries (1)
| Q8LDU4 |
RCCR_ARATH
Arabidopsis thaliana
Red chlorophyll catabolite reductase, chloroplastic
|
PDB Structure
| PDB | 3AGB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the substrate-bound forms of red chlorophyll catabolite reductase: implications for site-specific and stereospecific reaction
J.Mol.Biol.
|