CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family |
Enzyme Information
| 2.7.1.164 |
O-phosphoseryl-tRNA(Sec) kinase.
based on mapping to UniProt Q58933
ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
-!- In archaea and eukarya selenocysteine formation is achieved by a two- step process: O-phosphoseryl-tRNA(Sec) kinase (PSTK) phosphorylates the endogenous L-seryl-tRNA(Sec) to O-phospho-L-seryl-tRNA(Sec), and then this misacylated amino acid-tRNA species is converted to L-selenocysteinyl-tRNA(Sec) by EC 2.9.1.2. -!- Formerly EC 2.7.1.n3.
|
UniProtKB Entries (1)
| Q58933 |
PSTK_METJA
Methanocaldococcus jannaschii DSM 2661
L-seryl-tRNA(Sec) kinase
|
PDB Structure
| PDB | 3ADC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
Mol.Cell
|
