CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
Superfamily | P-loop containing nucleotide triphosphate hydrolases |
Functional Family |
Enzyme Information
2.7.1.164 |
O-phosphoseryl-tRNA(Sec) kinase.
based on mapping to UniProt Q58933
ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
-!- In archaea and eukarya selenocysteine formation is achieved by a two- step process: O-phosphoseryl-tRNA(Sec) kinase (PSTK) phosphorylates the endogenous L-seryl-tRNA(Sec) to O-phospho-L-seryl-tRNA(Sec), and then this misacylated amino acid-tRNA species is converted to L-selenocysteinyl-tRNA(Sec) by EC 2.9.1.2. -!- Formerly EC 2.7.1.n3.
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UniProtKB Entries (1)
Q58933 |
PSTK_METJA
Methanocaldococcus jannaschii DSM 2661
L-seryl-tRNA(Sec) kinase
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PDB Structure
PDB | 3A4L |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA
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