CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P00343
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P00343
LDH_LACCA
Lactobacillus casei
L-lactate dehydrogenase

PDB Structure

PDB 2ZQZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase.
Arai, K., Ishimitsu, T., Fushinobu, S., Uchikoba, H., Matsuzawa, H., Taguchi, H.
Proteins
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